Palmitoylethanolamide and Cannabidiol Prevent Inflammation-induced...
“We aimed to examine, for the first time, the effect of cannabidiol (CBD) and palmitoylethanolamide (PEA) on the permeability of the human gastrointestinal tract in vitro, ex vivo, and in vivo....
View ArticleEffect of cannabis on weight and metabolism in first-episode non-affective...
“Recent evidence indicates a protective effect of cannabis on weight gain and related metabolic alterations. However, there are no previous studies on the long-term longitudinal effects of cannabis on...
View ArticleCannabinoid receptor 2 deficiency exacerbates inflammation and neutrophil...
“Cannabinoid receptor (CB)2 is an immune cell-localized GPCR that has been hypothesized to regulate the magnitude of inflammatory responses. However, there is currently no consensus as to the...
View ArticleDecreased Expression of Cannabinoid Receptors in the Eutopic and Ectopic...
“Adenomyosis is a common gynecologic benign disease that may have a life-long negative impact on women. Previous studies have indicated that the endocannabinoid system may participate in the progress...
View ArticleCannabis Oil Use by Adolescents and Young Adults With Inflammatory Bowel...
“The aim of the study was to describe use of oral or sublingual cannabis oil (CO) by adolescent and young adult patients with inflammatory bowel disease (IBD). METHODS: A descriptive study of IBD...
View ArticleIntractable Generalized Epilepsy: Therapeutic Approaches.
“PURPOSE OF REVIEW: To summarize recent developments in therapeutic options, both medical and surgical, for patients with drug-resistant generalized epilepsy syndromes, which continue to be a...
View ArticleLung alveolar tissue destruction and protein citrullination in diesel exhaust...
“Humanity faces an increasing impact of air pollution worldwide, including threats to human health. Air pollutants prompt and promote chronic inflammation, tumourigenesis, autoimmune and other...
View ArticleCBN: The cancer fighting Cannabinoid
“CBN, cannabinol, is a mildly psychoactive cannabinoid found within the cannabis plant. We examine the very complex mechanisms that give allowance for this cannabinoids entrance into the cell membrane...
View ArticleCrystal Structure of the Human Cannabinoid Receptor CB2
“The cannabinoid receptor CB2 is predominately expressed in the immune system, and selective modulation of CB2 without the psychoactivity of CB1 has therapeutic potential in inflammatory, fibrotic,...
View ArticleComplete biosynthesis of cannabinoids and their unnatural analogues in yeast
“Cannabis sativa L. has been cultivated and used around the globe for its medicinal properties for millennia. Some cannabinoids, the hallmark constituents of Cannabis, and their analogues have been...
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ソナのパッシブにはAAキャンセルがある あとQのオーラ効果である追加ダメージはタワーに乗らないが、パッシブQの追加ダメージはタワーに乗る よってパッシブ2スタックの時にAAQAAでタワーに効率よくダメージを入れることが出来る
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ブランドのQのモーション中にフラッシュするとフラッシュ先でQが打てる かなり上級者向けコンボになるが、上手く距離を調整してこれを利用すると Q→フラッシュ→Eとやると、Eが当たってからQが当たるからスタンが入るし、Qの発生が早いから相手が逃げにくい ブランドのRはチャンピオン優先だけでなく、スタックを最大にするように(スタック数が多いチャンプを優先して)跳ねる...
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トリスのQは効果時間中にもCDRが解消されるタイプのスキルだからデータ上は20~16s(スキルLv1~5の数字)でも実際は効果時間7s引いて13~9sで再使用出来る。 更にCDRは20~16sを基準に適用されるから、普通のCD13~9sのスキルよりもCDRの恩恵を多く受ける 例えば20%CDRのとき、普通のCD13~9sのスキルは10.4s~7.2sになるけどトリスのQは9s~5.8sになる。 1
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